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SMILES: CC(Oc1c(N)ncc2c(coc12)-c1cnn(c1)C1CCNCC1)c1c(Cl)cccc1Cl

InChI Key: InChIKey=KMRLQWOJFKOHFR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437178   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50437178
PNG
(CHEMBL2401835)
Show SMILES CC(Oc1c(N)ncc2c(coc12)-c1cnn(c1)C1CCNCC1)c1c(Cl)cccc1Cl
Show InChI InChI=1S/C23H23Cl2N5O2/c1-13(20-18(24)3-2-4-19(20)25)32-22-21-16(10-28-23(22)26)17(12-31-21)14-9-29-30(11-14)15-5-7-27-8-6-15/h2-4,9-13,15,27H,5-8H2,1H3,(H2,26,28)
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n/an/a 220n/an/an/an/an/an/a



OSI Pharmaceuticals, LLC

Curated by ChEMBL


Assay Description
Inhibition of cMET (unknown origin) using biotinylated poly(Glu,Tyr) as substrate after 60 mins

Bioorg Med Chem Lett 23: 4381-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.05.074
BindingDB Entry DOI: 10.7270/Q2RB7601
More data for this
Ligand-Target Pair