BDBM50437638 CHEMBL2407661

SMILES: O=C(NCc1ccccc1)[C@@]1(Cc2ccccc2)OC(=O)N(Cc2ccccc2)C1=O

InChI Key: InChIKey=FYDFQSYCFUBSKB-RUZDIDTESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50437638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50437638 (CHEMBL2407661) Show SMILES O=C(NCc1ccccc1)[C@@]1(Cc2ccccc2)OC(=O)N(Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C25H22N2O4/c28-22(26-17-20-12-6-2-7-13-20)25(16-19-10-4-1-5-11-19)23(29)27(24(30)31-25)18-21-14-8-3-9-15-21/h1-15H,16-18H2,(H,26,28)/t25-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at mineralocorticoid receptor (unknown origin) by PathHunter assay				Bioorg Med Chem Lett 24: 1681-4 (2014) Article DOI: 10.1016/j.bmcl.2014.02.057 BindingDB Entry DOI: 10.7270/Q2N87C9H
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50437638 (CHEMBL2407661) Show SMILES O=C(NCc1ccccc1)[C@@]1(Cc2ccccc2)OC(=O)N(Cc2ccccc2)C1=O |r| Show InChI InChI=1S/C25H22N2O4/c28-22(26-17-20-12-6-2-7-13-20)25(16-19-10-4-1-5-11-19)23(29)27(24(30)31-25)18-21-14-8-3-9-15-21/h1-15H,16-18H2,(H,26,28)/t25-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human mineralocorticoid receptor assessed as inhibition of binding to coactivator peptide by NH Pro assay				Bioorg Med Chem Lett 23: 4388-92 (2013) Article DOI: 10.1016/j.bmcl.2013.05.077 BindingDB Entry DOI: 10.7270/Q269751R
					More data for this Ligand-Target Pair