BDBM50437779 CHEMBL2409682

SMILES: C[C@]1(CS(=O)(=O)N2CCC(CC2)Oc2ccc(OCc3ccccc3)cc2)NC(=O)NC1=O

InChI Key: InChIKey=HEKVSVDHQDDIEK-HSZRJFAPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50437779   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50437779 (CHEMBL2409682) Show SMILES C[C@]1(CS(=O)(=O)N2CCC(CC2)Oc2ccc(OCc3ccccc3)cc2)NC(=O)NC1=O |r| Show InChI InChI=1S/C23H27N3O6S/c1-23(21(27)24-22(28)25-23)16-33(29,30)26-13-11-20(12-14-26)32-19-9-7-18(8-10-19)31-15-17-5-3-2-4-6-17/h2-10,20H,11-16H2,1H3,(H2,24,25,27,28)/t23-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	671	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP-14 using Mca-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH2 as substrate after 20 hrs by fluorescence assay				Bioorg Med Chem Lett 23: 4705-12 (2013) Article DOI: 10.1016/j.bmcl.2013.05.089 BindingDB Entry DOI: 10.7270/Q2WS8VNH
					More data for this Ligand-Target Pair