BDBM50438110 CHEMBL2409734

SMILES: FC1(F)CC[C@@H]2OC(NS(=O)(=O)[C@@H]2C1)=NC1CCCCC1

InChI Key: InChIKey=MIESSTPUAJMNBR-WDEREUQCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50438110 (CHEMBL2409734) Show SMILES FC1(F)CC[C@@H]2OC(NS(=O)(=O)[C@@H]2C1)=NC1CCCCC1 |r,w:14.16| Show InChI InChI=1S/C13H20F2N2O3S/c14-13(15)7-6-10-11(8-13)21(18,19)17-12(20-10)16-9-4-2-1-3-5-9/h9-11H,1-8H2,(H,16,17)/t10-,11+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	234	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Deutschland GmbH Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1				Bioorg Med Chem Lett 23: 4685-91 (2013) Article DOI: 10.1016/j.bmcl.2013.05.102 BindingDB Entry DOI: 10.7270/Q2BV7J2H
					More data for this Ligand-Target Pair