BDBM50438276 CHEMBL2408579

SMILES: Cc1cccc(Nc2ncc3C(=O)C(C)(C)CCc3n2)c1

InChI Key: InChIKey=AVTLMBPIMBWFQW-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50438276 (CHEMBL2408579) Show SMILES Cc1cccc(Nc2ncc3C(=O)C(C)(C)CCc3n2)c1 Show InChI InChI=1S/C17H19N3O/c1-11-5-4-6-12(9-11)19-16-18-10-13-14(20-16)7-8-17(2,3)15(13)21/h4-6,9-10H,7-8H2,1-3H3,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	694	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR5 expressed in CHO cells assessed as increase of L-quisqualate-induced intracellular cAMP accumulation t...				Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8
					More data for this Ligand-Target Pair