BDBM50438302 CHEMBL2408562

SMILES: Fc1cc(Nc2ncc3C(=O)CCCc3n2)cc(c1)C#N

InChI Key: InChIKey=AYYDRSULPHUZRF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438302   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50438302 (CHEMBL2408562) Show SMILES Fc1cc(Nc2ncc3C(=O)CCCc3n2)cc(c1)C#N Show InChI InChI=1S/C15H11FN4O/c16-10-4-9(7-17)5-11(6-10)19-15-18-8-12-13(20-15)2-1-3-14(12)21/h4-6,8H,1-3H2,(H,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merz Pharmaceuticals GmbH Curated by ChEMBL					Assay Description Negative allosteric modulation of human mGluR5 expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular cAMP accumulation...				Bioorg Med Chem Lett 23: 4493-500 (2013) Article DOI: 10.1016/j.bmcl.2013.06.049 BindingDB Entry DOI: 10.7270/Q2KD20B8
					More data for this Ligand-Target Pair