BDBM50438380 CHEMBL2413608

SMILES: COc1cc(CN2c3ccccc3C(=O)N3C[C@H](O)C[C@H]3C2=O)cc(OC)c1OC

InChI Key: InChIKey=KWJXQSQVOWQQJY-PBHICJAKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50438380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50438380 (CHEMBL2413608) Show SMILES COc1cc(CN2c3ccccc3C(=O)N3C[C@H](O)C[C@H]3C2=O)cc(OC)c1OC |r| Show InChI InChI=1S/C22H24N2O6/c1-28-18-8-13(9-19(29-2)20(18)30-3)11-23-16-7-5-4-6-15(16)21(26)24-12-14(25)10-17(24)22(23)27/h4-9,14,17,25H,10-12H2,1-3H3/t14-,17+/m1/s1	MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	376	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 mins				Bioorg Med Chem 21: 4485-93 (2013) Article DOI: 10.1016/j.bmc.2013.05.031 BindingDB Entry DOI: 10.7270/Q2P55PXT
					More data for this Ligand-Target Pair