BDBM50438496 CHEMBL2414825

SMILES: OC[C@H]1O[C@@H](CNCc2ccc(Cl)c(Cl)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=ZDHISULVBUIOFC-MEBFFEOJSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50438496   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
alpha-Glucosidase (α-Glucosidase) (Rattus norvegicus (Rat))	BDBM50438496 (CHEMBL2414825) Show SMILES OC[C@H]1O[C@@H](CNCc2ccc(Cl)c(Cl)c2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C14H19Cl2NO5/c15-8-2-1-7(3-9(8)16)4-17-5-10-12(19)14(21)13(20)11(6-18)22-10/h1-3,10-14,17-21H,4-6H2/t10-,11+,12-,13+,14+/m0/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of rat intestinal sucrase using sucrose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
					More data for this Ligand-Target Pair
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM50438496 (CHEMBL2414825) Show SMILES OC[C@H]1O[C@@H](CNCc2ccc(Cl)c(Cl)c2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C14H19Cl2NO5/c15-8-2-1-7(3-9(8)16)4-17-5-10-12(19)14(21)13(20)11(6-18)22-10/h1-3,10-14,17-21H,4-6H2/t10-,11+,12-,13+,14+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
					More data for this Ligand-Target Pair
Acidic alpha-glucosidase (Rattus norvegicus)	BDBM50438496 (CHEMBL2414825) Show SMILES OC[C@H]1O[C@@H](CNCc2ccc(Cl)c(Cl)c2)[C@H](O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C14H19Cl2NO5/c15-8-2-1-7(3-9(8)16)4-17-5-10-12(19)14(21)13(20)11(6-18)22-10/h1-3,10-14,17-21H,4-6H2/t10-,11+,12-,13+,14+/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.21E+5	n/a	n/a	n/a	n/a	n/a	n/a
Xi'an Jiaotong University Curated by ChEMBL					Assay Description Inhibition of rat intestinal maltase using maltose as substrate assessed as D-glucose release from substrate preincubated for 15 mins measured after ...				Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24
					More data for this Ligand-Target Pair