BDBM50438663 CHEMBL1452451

SMILES: [O-][N+](=O)c1ccc(OCCCn2cncn2)cc1

InChI Key: InChIKey=AOOIHLJFOSMZBC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438663   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme Oxygenase 2 (HO-2) (Rattus norvegicus (rat))	BDBM50438663 (CHEMBL1452451) Show SMILES [O-][N+](=O)c1ccc(OCCCn2cncn2)cc1 Show InChI InChI=1S/C11H12N4O3/c16-15(17)10-2-4-11(5-3-10)18-7-1-6-14-9-12-8-13-14/h2-5,8-9H,1,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of HO2 in Sprague-Dawley rat brain microsomal fraction assessed as reduction in bilirubin formation incubated for 60 mins by double beam s...				Eur J Med Chem 96: 162-72 (2015) Article DOI: 10.1016/j.ejmech.2015.04.003 BindingDB Entry DOI: 10.7270/Q2KH0Q16
					More data for this Ligand-Target Pair
Heme Oxygenase 1 (HO-1) (Rattus norvegicus (rat))	BDBM50438663 (CHEMBL1452451) Show SMILES [O-][N+](=O)c1ccc(OCCCn2cncn2)cc1 Show InChI InChI=1S/C11H12N4O3/c16-15(17)10-2-4-11(5-3-10)18-7-1-6-14-9-12-8-13-14/h2-5,8-9H,1,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat spleen microsomal HO-1 assessed as bilirubin formation after 60 mins by spectrophotometric analysis				Bioorg Med Chem 21: 5145-53 (2013) Article DOI: 10.1016/j.bmc.2013.06.040 BindingDB Entry DOI: 10.7270/Q2FF3TSH
					More data for this Ligand-Target Pair