BDBM50438747 CHEMBL2414787

SMILES: CC(C)N[C@@H](CC(C)(C)C)C(=O)N[C@H]1CC[C@@H]2CN(C[C@H]12)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=VFERXZCIWTVZIB-SEVLPDGMSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50438747 (CHEMBL2414787) Show SMILES CC(C)N[C@@H](CC(C)(C)C)C(=O)N[C@H]1CC[C@@H]2CN(C[C@H]12)S(=O)(=O)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C24H36F3N3O3S/c1-15(2)28-21(12-23(3,4)5)22(31)29-20-11-6-16-13-30(14-19(16)20)34(32,33)18-9-7-17(8-10-18)24(25,26)27/h7-10,15-16,19-21,28H,6,11-14H2,1-5H3,(H,29,31)/t16-,19+,20+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience Research, AbbVie, 1 N Waukegan Road, North Chicago, IL 60064, United States. xenia.b.searle@abbvie.com Curated by ChEMBL					Assay Description Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under depolarized condition by whole cell patch-clamp manual electrophysiology assa...				Bioorg Med Chem Lett 23: 4857-61 (2013) Article DOI: 10.1016/j.bmcl.2013.06.074 BindingDB Entry DOI: 10.7270/Q2280915
					More data for this Ligand-Target Pair
Voltage-dependent N-type calcium channel subunit alpha-1B (Rattus norvegicus (Rat))	BDBM50438747 (CHEMBL2414787) Show SMILES CC(C)N[C@@H](CC(C)(C)C)C(=O)N[C@H]1CC[C@@H]2CN(C[C@H]12)S(=O)(=O)c1ccc(cc1)C(F)(F)F |r| Show InChI InChI=1S/C24H36F3N3O3S/c1-15(2)28-21(12-23(3,4)5)22(31)29-20-11-6-16-13-30(14-19(16)20)34(32,33)18-9-7-17(8-10-18)24(25,26)27/h7-10,15-16,19-21,28H,6,11-14H2,1-5H3,(H,29,31)/t16-,19+,20+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Neuroscience Research, AbbVie, 1 N Waukegan Road, North Chicago, IL 60064, United States. xenia.b.searle@abbvie.com Curated by ChEMBL					Assay Description Inhibition of rat N-type Cav2.2 channel expressed in HEK293 cells under hyperpolarized condition by whole cell patch-clamp manual electrophysiology a...				Bioorg Med Chem Lett 23: 4857-61 (2013) Article DOI: 10.1016/j.bmcl.2013.06.074 BindingDB Entry DOI: 10.7270/Q2280915
					More data for this Ligand-Target Pair