BDBM50439307 CHEMBL2419517

SMILES: CCCn1cc(cn1)S(=O)(=O)c1ccc(CNC(=O)N2Cc3ccncc3C2)cc1

InChI Key: InChIKey=BIYHERJIIMZOGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439307   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide phosphoribosyltransferase (Homo sapiens (Human))	BDBM50439307 (CHEMBL2419517) Show SMILES CCCn1cc(cn1)S(=O)(=O)c1ccc(CNC(=O)N2Cc3ccncc3C2)cc1 Show InChI InChI=1S/C21H23N5O3S/c1-2-9-26-15-20(12-24-26)30(28,29)19-5-3-16(4-6-19)10-23-21(27)25-13-17-7-8-22-11-18(17)14-25/h3-8,11-12,15H,2,9-10,13-14H2,1H3,(H,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Inc Curated by ChEMBL					Assay Description Inhibition of human NAMPT using NAM/PRPP as substrate incubated for 15 mins prior to substrate addition measured after 30 mins by mass spectrometric ...				Bioorg Med Chem Lett 23: 4875-85 (2013) Article DOI: 10.1016/j.bmcl.2013.06.090 BindingDB Entry DOI: 10.7270/Q25T3MWP
					More data for this Ligand-Target Pair