BDBM50439414 CHEMBL2420550
SMILES: CS(=O)(=O)c1cc(NC(=O)Cc2ccccc2Cl)ccc1F
InChI Key: InChIKey=WDKOZUZJQIVTGI-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
G protein-activated inward rectifier potassium channel 1 (Homo sapiens (Human)) | BDBM50439414 (CHEMBL2420550) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Activation of GIRK1/2 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay | Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
G protein-activated inward rectifier potassium channel 4 (Homo sapiens (Human)) | BDBM50439414 (CHEMBL2420550) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Vanderbilt University Curated by ChEMBL | Assay Description Activation of GIRK1/4 (unknown origin) transfected in HEK293 cells after 4 mins by thallium flux-based fluorescence assay | Bioorg Med Chem Lett 23: 5195-8 (2013) Article DOI: 10.1016/j.bmcl.2013.07.002 BindingDB Entry DOI: 10.7270/Q28K7BG1 | |||||||||||
More data for this Ligand-Target Pair |