BDBM50439463 CHEMBL2420911

SMILES: C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12

InChI Key: InChIKey=ZXMGQAIKNOIWHC-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50439463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of ABL (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha 1 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of RSK1 (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha 5 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of MSK1 (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of AKT1 (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK1 (unknown origin) by Z'-Lyte assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.83E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of MET (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase CHK2 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CHK2 (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of PKD2 (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 5 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of PRAK (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of AURA (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of CK1delta (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50439463 (CHEMBL2420911) Show SMILES C1CNCC2(C1)CCN(CC2)c1ncnc2nc[nH]c12 Show InChI InChI=1S/C14H20N6/c1-2-14(8-15-5-1)3-6-20(7-4-14)13-11-12(17-9-16-11)18-10-19-13/h9-10,15H,1-8H2,(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of ERK2 (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair