BDBM50439465 CHEMBL2420904

SMILES: OC(=O)C1CCC2(CCN(CC2)c2ncnc3nc[nH]c23)NC1

InChI Key: InChIKey=DKDRBYGOIPHLMM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50439465   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50439465 (CHEMBL2420904) Show SMILES OC(=O)C1CCC2(CCN(CC2)c2ncnc3nc[nH]c23)NC1 Show InChI InChI=1S/C15H20N6O2/c22-14(23)10-1-2-15(20-7-10)3-5-21(6-4-15)13-11-12(17-8-16-11)18-9-19-13/h8-10,20H,1-7H2,(H,22,23)(H,16,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of AURA (unknown origin) by microfluidic mobility shift assay				Bioorg Med Chem 21: 5707-24 (2013) Article DOI: 10.1016/j.bmc.2013.07.021 BindingDB Entry DOI: 10.7270/Q2MW2JK5
					More data for this Ligand-Target Pair