BDBM50440053 CHEMBL2426104

SMILES: OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C(F)(F)F)c2ccccc2[nH]c1=O

InChI Key: InChIKey=NTMPGUAYNNAYJT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50440053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2D (Rattus norvegicus (Rat))	BDBM50440053 (CHEMBL2426104) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C(F)(F)F)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClF3N3O4/c30-19-11-7-16(8-12-19)23-15-22(35-36(23)24(37)13-14-25(38)39)27-26(17-5-9-18(10-6-17)29(31,32)33)20-3-1-2-4-21(20)34-28(27)40/h1-12,23H,13-15H2,(H,34,40)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
NMDA receptor subunit N2A (GluN2A) (Rattus norvegicus (Rat))	BDBM50440053 (CHEMBL2426104) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C(F)(F)F)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClF3N3O4/c30-19-11-7-16(8-12-19)23-15-22(35-36(23)24(37)13-14-25(38)39)27-26(17-5-9-18(10-6-17)29(31,32)33)20-3-1-2-4-21(20)34-28(27)40/h1-12,23H,13-15H2,(H,34,40)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2A receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50440053 (CHEMBL2426104) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C(F)(F)F)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClF3N3O4/c30-19-11-7-16(8-12-19)23-15-22(35-36(23)24(37)13-14-25(38)39)27-26(17-5-9-18(10-6-17)29(31,32)33)20-3-1-2-4-21(20)34-28(27)40/h1-12,23H,13-15H2,(H,34,40)(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2B receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair
NMDA receptor subunit 2C (GluN2C) (Rattus norvegicus (Rat))	BDBM50440053 (CHEMBL2426104) Show SMILES OC(=O)CCC(=O)N1N=C(CC1c1ccc(Cl)cc1)c1c(-c2ccc(cc2)C(F)(F)F)c2ccccc2[nH]c1=O |c:8| Show InChI InChI=1S/C29H21ClF3N3O4/c30-19-11-7-16(8-12-19)23-15-22(35-36(23)24(37)13-14-25(38)39)27-26(17-5-9-18(10-6-17)29(31,32)33)20-3-1-2-4-21(20)34-28(27)40/h1-12,23H,13-15H2,(H,34,40)(H,38,39)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by ChEMBL					Assay Description Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp method				J Med Chem 56: 6434-56 (2013) Article DOI: 10.1021/jm400652r BindingDB Entry DOI: 10.7270/Q26H4JTJ
					More data for this Ligand-Target Pair