BDBM50440494 CHEMBL2426152

SMILES: CC(C)(C(c1ccccc1)c1ccc2[nH]ccc2c1)C(=O)Nc1nccs1

InChI Key: InChIKey=UUSCTTLEOKMUJK-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440494   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50440494 (CHEMBL2426152) Show SMILES CC(C)(C(c1ccccc1)c1ccc2[nH]ccc2c1)C(=O)Nc1nccs1 Show InChI InChI=1S/C22H21N3OS/c1-22(2,20(26)25-21-24-12-13-27-21)19(15-6-4-3-5-7-15)17-8-9-18-16(14-17)10-11-23-18/h3-14,19,23H,1-2H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Binding affinity to glucocorticoid receptor-LBD (unknown origin) by fluorescence polarization assay				Bioorg Med Chem Lett 23: 5571-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.049 BindingDB Entry DOI: 10.7270/Q2QC04Z4
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50440494 (CHEMBL2426152) Show SMILES CC(C)(C(c1ccccc1)c1ccc2[nH]ccc2c1)C(=O)Nc1nccs1 Show InChI InChI=1S/C22H21N3OS/c1-22(2,20(26)25-21-24-12-13-27-21)19(15-6-4-3-5-7-15)17-8-9-18-16(14-17)10-11-23-18/h3-14,19,23H,1-2H3,(H,24,25,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Transrepression of glucocorticoid receptor in human A549 cells assessed as inhibition of PMA-induced AP-1 activity by luciferase reporter gene assay				Bioorg Med Chem Lett 23: 5571-4 (2013) Article DOI: 10.1016/j.bmcl.2013.08.049 BindingDB Entry DOI: 10.7270/Q2QC04Z4
					More data for this Ligand-Target Pair