BDBM50440509 CHEMBL2426179

SMILES: Clc1ccc(NC(=O)Nc2cccc(n2)-c2ccncc2)cc1Cl

InChI Key: InChIKey=IQVIVUCZIJXEDE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bloom syndrome protein (Homo sapiens (Human))	BDBM50440509 (CHEMBL2426179) Show SMILES Clc1ccc(NC(=O)Nc2cccc(n2)-c2ccncc2)cc1Cl Show InChI InChI=1S/C17H12Cl2N4O/c18-13-5-4-12(10-14(13)19)21-17(24)23-16-3-1-2-15(22-16)11-6-8-20-9-7-11/h1-10H,(H2,21,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair