BDBM50440512 CHEMBL2426187

SMILES: Clc1ccc(Nc2c(Nc3nnc(s3)-c3ccncc3)c(=O)c2=O)cc1Cl

InChI Key: InChIKey=HIKDEHZLRZETSG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bloom syndrome protein (Homo sapiens (Human))	BDBM50440512 (CHEMBL2426187) Show SMILES Clc1ccc(Nc2c(Nc3nnc(s3)-c3ccncc3)c(=O)c2=O)cc1Cl Show InChI InChI=1S/C17H9Cl2N5O2S/c18-10-2-1-9(7-11(10)19)21-12-13(15(26)14(12)25)22-17-24-23-16(27-17)8-3-5-20-6-4-8/h1-7,21H,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair