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SMILES: Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1F

InChI Key: InChIKey=XGDXUHMMNWGJIB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440529   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RecQ-like DNA helicase BLM


(Homo sapiens (Human))		BDBM50440529
PNG
(CHEMBL2426166)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1F
Show InChI InChI=1S/C14H9F2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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MMDB

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PubMed
n/an/a 8.90E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay

Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair