BDBM50440535 CHEMBL2426171

SMILES: FC(F)(F)c1cc(NC(=O)Nc2nnc(s2)-c2ccncc2)ccc1-n1cncn1

InChI Key: InChIKey=TYSWQVDVSLVQDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bloom syndrome protein (Homo sapiens (Human))	BDBM50440535 (CHEMBL2426171) Show SMILES FC(F)(F)c1cc(NC(=O)Nc2nnc(s2)-c2ccncc2)ccc1-n1cncn1 Show InChI InChI=1S/C17H11F3N8OS/c18-17(19,20)12-7-11(1-2-13(12)28-9-22-8-23-28)24-15(29)25-16-27-26-14(30-16)10-3-5-21-6-4-10/h1-9H,(H2,24,25,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair