BDBM50440888 CHEMBL2429888

SMILES: N#Cc1cccc(c1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1

InChI Key: InChIKey=AWPGEMDEIDCXMW-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440888   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440888 (CHEMBL2429888) Show SMILES N#Cc1cccc(c1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C22H14N6/c23-14-16-3-1-4-18(12-16)20-8-9-21-25-26-22(28(21)27-20)13-15-6-7-19-17(11-15)5-2-10-24-19/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal His-6-tagged human recombinant c-Met (974 to 1390) using Ac-ARDMYDKEYYSVHNK as substrate by spectrophotometric assay				J Med Chem 56: 6651-65 (2013) Article DOI: 10.1021/jm400926x BindingDB Entry DOI: 10.7270/Q2HM59WR
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50440888 (CHEMBL2429888) Show SMILES N#Cc1cccc(c1)-c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 Show InChI InChI=1S/C22H14N6/c23-14-16-3-1-4-18(12-16)20-8-9-21-25-26-22(28(21)27-20)13-15-6-7-19-17(11-15)5-2-10-24-19/h1-12H,13H2	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of c-Met autophosphorylation in human A549 cells after 1 hr by ELISA				J Med Chem 56: 6651-65 (2013) Article DOI: 10.1021/jm400926x BindingDB Entry DOI: 10.7270/Q2HM59WR
					More data for this Ligand-Target Pair