BDBM50440908 CHEMBL2431912

SMILES: Cn1cccc1C(=O)N1CCCc2cc(ccc2C1)C(=O)NO

InChI Key: InChIKey=LJJCJABXEFNCNY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50440908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3 (Homo sapiens (Human))	BDBM50440908 (CHEMBL2431912) Show SMILES Cn1cccc1C(=O)N1CCCc2cc(ccc2C1)C(=O)NO Show InChI InChI=1S/C17H19N3O3/c1-19-8-3-5-15(19)17(22)20-9-2-4-12-10-13(16(21)18-23)6-7-14(12)11-20/h3,5-8,10,23H,2,4,9,11H2,1H3,(H,18,21)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of full length C-terminal His6x-tagged recombinant human HDAC3 expressed in baculovirus using Arg-His-Lys-Lys (Ac) as substrate after 1 hr...				J Med Chem 56: 7201-11 (2013) Article DOI: 10.1021/jm400385r BindingDB Entry DOI: 10.7270/Q2862HX7
					More data for this Ligand-Target Pair