BDBM50441059 CHEMBL2430252

SMILES: Cc1[nH]c2c(CCC\C2=C2\C(=O)Nc3ccc(F)cc23)c1C(=O)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=HDZYCUZNQKCOGY-DAFNUICNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441059   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50441059 (CHEMBL2430252) Show SMILES Cc1[nH]c2c(CCC\C2=C2\C(=O)Nc3ccc(F)cc23)c1C(=O)N1CCC(CC1)N1CCCCC1 Show InChI InChI=1S/C28H33FN4O2/c1-17-24(28(35)33-14-10-19(11-15-33)32-12-3-2-4-13-32)20-6-5-7-21(26(20)30-17)25-22-16-18(29)8-9-23(22)31-27(25)34/h8-9,16,19,30H,2-7,10-15H2,1H3,(H,31,34)/b25-21-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Technology Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta (unknown origin)				Bioorg Med Chem Lett 23: 5630-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.037 BindingDB Entry DOI: 10.7270/Q23F4R30
					More data for this Ligand-Target Pair