BDBM50441063 CHEMBL2430248

SMILES: Cc1[nH]c2c(CCC\C2=C2\C(=O)Nc3ccc(F)cc23)c1C(=O)NCCCN1CCOCC1

InChI Key: InChIKey=MWDKQVZICDCEDA-PYCFMQQDSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441063   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50441063 (CHEMBL2430248) Show SMILES Cc1[nH]c2c(CCC\C2=C2\C(=O)Nc3ccc(F)cc23)c1C(=O)NCCCN1CCOCC1 Show InChI InChI=1S/C25H29FN4O3/c1-15-21(24(31)27-8-3-9-30-10-12-33-13-11-30)17-4-2-5-18(23(17)28-15)22-19-14-16(26)6-7-20(19)29-25(22)32/h6-7,14,28H,2-5,8-13H2,1H3,(H,27,31)(H,29,32)/b22-18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University of Technology Curated by ChEMBL					Assay Description Inhibition of PDGFR-beta (unknown origin)				Bioorg Med Chem Lett 23: 5630-3 (2013) Article DOI: 10.1016/j.bmcl.2013.08.037 BindingDB Entry DOI: 10.7270/Q23F4R30
					More data for this Ligand-Target Pair