Found 3 hits for monomerid = 50441122 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lactate dehydrogenase B (LDHB)
(Homo sapiens (Human)) | BDBM50441122
(CHEMBL2430730)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C)c(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060 BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this Ligand-Target Pair | |
Lactate dehydrogenase A (LDHA)
(Homo sapiens (Human)) | BDBM50441122
(CHEMBL2430730)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C)c(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate assessed as dis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060 BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this Ligand-Target Pair | |
Lactate dehydrogenase A (LDHA)
(Homo sapiens (Human)) | BDBM50441122
(CHEMBL2430730)Show SMILES C[C@@H](Nc1nc(cnc1N)-c1ccc(C)c(c1)C(O)=O)c1ccccc1 |r| Show InChI InChI=1S/C20H20N4O2/c1-12-8-9-15(10-16(12)20(25)26)17-11-22-18(21)19(24-17)23-13(2)14-6-4-3-5-7-14/h3-11,13H,1-2H3,(H2,21,22)(H,23,24)(H,25,26)/t13-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a |
Genentech
Curated by ChEMBL
| Assay Description Binding affinity to human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli by surface plasmon resonance analysis... |
Bioorg Med Chem Lett 23: 5533-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.08.060 BindingDB Entry DOI: 10.7270/Q2668FM1 |
More data for this Ligand-Target Pair | |