BDBM50441414 CHEMBL2435965

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nccc(n4)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=OKJTTYWLYKAMBD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50441414 (CHEMBL2435965) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nccc(n4)-c4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C34H31F2N5O4/c1-43-31-20-25-28(21-32(31)44-18-4-17-41-15-2-3-16-41)37-14-12-29(25)45-30-10-9-24(19-26(30)36)39-34(42)33-38-13-11-27(40-33)22-5-7-23(35)8-6-22/h5-14,19-21H,2-4,15-18H2,1H3,(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 69: 77-89 (2013) Article DOI: 10.1016/j.ejmech.2013.08.019 BindingDB Entry DOI: 10.7270/Q2BR8TKW
					More data for this Ligand-Target Pair