BDBM50441416 CHEMBL2435975

SMILES: COc1cc2c(Oc3ccc(NC(=O)c4nccc(n4)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCOCC1

InChI Key: InChIKey=RBUJKCIMCCHILL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441416   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50441416 (CHEMBL2435975) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4nccc(n4)-c4ccccc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H32FN5O5/c1-42-31-21-25-28(22-32(31)44-17-5-14-40-15-18-43-19-16-40)36-13-11-29(25)45-30-9-8-24(20-26(30)35)38-34(41)33-37-12-10-27(39-33)23-6-3-2-4-7-23/h2-4,6-13,20-22H,5,14-19H2,1H3,(H,38,41)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysis				Eur J Med Chem 69: 77-89 (2013) Article DOI: 10.1016/j.ejmech.2013.08.019 BindingDB Entry DOI: 10.7270/Q2BR8TKW
					More data for this Ligand-Target Pair