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SMILES: O=C(COc1ccc(cc1)-c1ccccc1)NNC(=S)NCc1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=DCPYPUFLETUZTK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441584   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
A disintegrin and metalloproteinase with thrombospondin motifs 5


(Homo sapiens (Human))		BDBM50441584
PNG
(CHEMBL2437179)
Show SMILES O=C(COc1ccc(cc1)-c1ccccc1)NNC(=S)NCc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C28H25N3O2S/c32-27(20-33-26-17-15-25(16-18-26)23-9-5-2-6-10-23)30-31-28(34)29-19-21-11-13-24(14-12-21)22-7-3-1-4-8-22/h1-18H,19-20H2,(H,30,32)(H2,29,31,34)
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PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...

Eur J Med Chem 69: 244-61 (2013)


Article DOI: 10.1016/j.ejmech.2013.08.027
BindingDB Entry DOI: 10.7270/Q2J967TM
More data for this
Ligand-Target Pair