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SMILES: Clc1ccc(OCC(=O)NNC(=S)NCc2ccc(cc2)-c2ccccc2)cc1

InChI Key: InChIKey=VMHMVVSNDAABQL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441619   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
A disintegrin and metalloproteinase with thrombospondin motifs 5


(Homo sapiens (Human))		BDBM50441619
PNG
(CHEMBL2437189)
Show SMILES Clc1ccc(OCC(=O)NNC(=S)NCc2ccc(cc2)-c2ccccc2)cc1
Show InChI InChI=1S/C22H20ClN3O2S/c23-19-10-12-20(13-11-19)28-15-21(27)25-26-22(29)24-14-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-13H,14-15H2,(H,25,27)(H2,24,26,29)
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Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured a...

Eur J Med Chem 69: 244-61 (2013)


Article DOI: 10.1016/j.ejmech.2013.08.027
BindingDB Entry DOI: 10.7270/Q2J967TM
More data for this
Ligand-Target Pair