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SMILES: CC(c1ccc(Cl)c(Cl)c1)n1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccnc(N)c3)CC2)c1=O

InChI Key: InChIKey=FPXHABRAFBDZTO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441650   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50441650
PNG
(CHEMBL2437418)
Show SMILES CC(c1ccc(Cl)c(Cl)c1)n1c2ccccc2n(C2CCN(CC2)C(=O)C2CCN(Cc3ccnc(N)c3)CC2)c1=O
Show InChI InChI=1S/C32H36Cl2N6O2/c1-21(24-6-7-26(33)27(34)19-24)39-28-4-2-3-5-29(28)40(32(39)42)25-11-16-38(17-12-25)31(41)23-9-14-37(15-10-23)20-22-8-13-36-30(35)18-22/h2-8,13,18-19,21,23,25H,9-12,14-17,20H2,1H3,(H2,35,36)
UniProtKB/SwissProt

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UniChem

Similars
Article
PubMed
 77n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates

Bioorg Med Chem Lett 23: 6001-3 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.012
BindingDB Entry DOI: 10.7270/Q2542Q1F
More data for this
Ligand-Target Pair