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SMILES: Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3n(Cc3ccc(Cl)cc3)c2=O)ccn1

InChI Key: InChIKey=ZWVIFSPZUJVHGF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441656   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(GUINEA PIG)		BDBM50441656
PNG
(CHEMBL2437414)
Show SMILES Nc1cc(CN2CCC(CC2)C(=O)N2CCC(CC2)n2c3ccccc3n(Cc3ccc(Cl)cc3)c2=O)ccn1
Show InChI InChI=1S/C31H35ClN6O2/c32-25-7-5-22(6-8-25)21-37-27-3-1-2-4-28(27)38(31(37)40)26-12-17-36(18-13-26)30(39)24-10-15-35(16-11-24)20-23-9-14-34-29(33)19-23/h1-9,14,19,24,26H,10-13,15-18,20-21H2,(H2,33,34)
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Similars
Article
PubMed
 12n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]-N-alpha-methyl histamine from histamine H3 receptor in guinea pig brain homogenates

Bioorg Med Chem Lett 23: 6001-3 (2013)


Article DOI: 10.1016/j.bmcl.2013.08.012
BindingDB Entry DOI: 10.7270/Q2542Q1F
More data for this
Ligand-Target Pair