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SMILES: CN(Cc1ccc(Cl)s1)c1cc(C)nc2nc(N)nn12

InChI Key: InChIKey=BWYATFCHPWUVFE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441760   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Bromodomain-containing protein 4


(Homo sapiens (Human))		BDBM50441760
PNG
(CHEMBL2436008)
Show SMILES CN(Cc1ccc(Cl)s1)c1cc(C)nc2nc(N)nn12
Show InChI InChI=1S/C12H13ClN6S/c1-7-5-10(19-12(15-7)16-11(14)17-19)18(2)6-8-3-4-9(13)20-8/h3-5H,6H2,1-2H3,(H2,14,17)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.80E+4n/an/an/an/an/an/a



The Institute of Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of His-tagged first bromodomain of BRD4 (unknown origin) using H-SGRGK(Ac)GGK(Ac)GLGK-(Ac)GGAK(Ac)RHRK(Biotin)-OH as substrate preincubate...

J Med Chem 56: 8073-88 (2013)


Article DOI: 10.1021/jm4011302
BindingDB Entry DOI: 10.7270/Q20C4X6S
More data for this
Ligand-Target Pair