BDBM50441981 CHEMBL2440570

SMILES: CS(=O)(=O)N1CCN(CC1)C(=S)SCc1cn(Cc2ccc(F)cc2)nn1

InChI Key: InChIKey=OPSFJFHAFAOANF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50441981   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50441981 (CHEMBL2440570) Show SMILES CS(=O)(=O)N1CCN(CC1)C(=S)SCc1cn(Cc2ccc(F)cc2)nn1 Show InChI InChI=1S/C16H20FN5O2S3/c1-27(23,24)22-8-6-20(7-9-22)16(25)26-12-15-11-21(19-18-15)10-13-2-4-14(17)5-3-13/h2-5,11H,6-10,12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zhengzhou University Curated by ChEMBL					Assay Description Inhibition of human recombinant LSD1 (157 to 852 aa) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay				J Med Chem 56: 8543-60 (2013) Article DOI: 10.1021/jm401002r BindingDB Entry DOI: 10.7270/Q2XD1333
					More data for this Ligand-Target Pair