BDBM50442280 CHEMBL2442132

SMILES: CC(Sc1cc(cnc1N)-c1cnn(c1)C1CCN(CC1)S(C)(=O)=O)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=KEMBGGTWJYJBHP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50442280 (CHEMBL2442132) Show SMILES CC(Sc1cc(cnc1N)-c1cnn(c1)C1CCN(CC1)S(C)(=O)=O)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C22H24Cl2FN5O2S2/c1-13(20-17(23)3-4-18(25)21(20)24)33-19-9-14(10-27-22(19)26)15-11-28-30(12-15)16-5-7-29(8-6-16)34(2,31)32/h3-4,9-13,16H,5-8H2,1-2H3,(H2,26,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				Bioorg Med Chem 21: 6804-20 (2013) Article DOI: 10.1016/j.bmc.2013.07.032 BindingDB Entry DOI: 10.7270/Q27P90TV
					More data for this Ligand-Target Pair