BDBM50442282 CHEMBL2442130

SMILES: CC(Sc1cc(cnc1N)-c1cnn(c1)C(=O)N(C)C)c1c(Cl)ccc(F)c1Cl

InChI Key: InChIKey=OSXGQHJTPWUDEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50442282 (CHEMBL2442130) Show SMILES CC(Sc1cc(cnc1N)-c1cnn(c1)C(=O)N(C)C)c1c(Cl)ccc(F)c1Cl Show InChI InChI=1S/C19H18Cl2FN5OS/c1-10(16-13(20)4-5-14(22)17(16)21)29-15-6-11(7-24-18(15)23)12-8-25-27(9-12)19(28)26(2)3/h4-10H,1-3H3,(H2,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISA				Bioorg Med Chem 21: 6804-20 (2013) Article DOI: 10.1016/j.bmc.2013.07.032 BindingDB Entry DOI: 10.7270/Q27P90TV
					More data for this Ligand-Target Pair