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SMILES: CCOC(=O)c1cc(nc2ccc3n(CC)ccc3c12)-c1ccccc1

InChI Key: InChIKey=PYLPOLKFNUFZTJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442332   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aromatase


(Homo sapiens (Human))		BDBM50442332
PNG
(CHEMBL2442771)
Show SMILES CCOC(=O)c1cc(nc2ccc3n(CC)ccc3c12)-c1ccccc1
Show InChI InChI=1S/C22H20N2O2/c1-3-24-13-12-16-20(24)11-10-18-21(16)17(22(25)26-4-2)14-19(23-18)15-8-6-5-7-9-15/h5-14H,3-4H2,1-2H3
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



University of Padova

Curated by ChEMBL


Assay Description
Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysis

J Med Chem 56: 7536-51 (2013)


Article DOI: 10.1021/jm400377z
BindingDB Entry DOI: 10.7270/Q2M046WV
More data for this
Ligand-Target Pair