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SMILES: CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=RRYZEJFQBYDTNH-SSSFQFABSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442480   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50442480
PNG
(CHEMBL2440380)
Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)cc1 |r|
Show InChI InChI=1S/C21H25ClO6/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)20-18(25)19(26)21(28-20)17(24)11-23/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19-,20+,21-/m1/s1
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Similars
Article
PubMed
n/an/an/an/a>5.00E+4n/an/an/an/a



National Taiwan University

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method

Bioorg Med Chem 21: 6282-91 (2013)


Article DOI: 10.1016/j.bmc.2013.08.067
BindingDB Entry DOI: 10.7270/Q29G5P80
More data for this
Ligand-Target Pair