BDBM50442488 CHEMBL2440374

SMILES: CC(C)(C)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)cc1

InChI Key: InChIKey=YWRADPUGRXUVRV-CSEOROSGSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442488   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50442488 (CHEMBL2440374) Show SMILES CC(C)(C)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C23H29ClO5/c1-23(2,3)16-7-4-13(5-8-16)10-15-11-14(6-9-17(15)24)21-19(27)20(28)22(29-21)18(26)12-25/h4-9,11,18-22,25-28H,10,12H2,1-3H3/t18-,19-,20-,21+,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method				Bioorg Med Chem 21: 6282-91 (2013) Article DOI: 10.1016/j.bmc.2013.08.067 BindingDB Entry DOI: 10.7270/Q29G5P80
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50442488 (CHEMBL2440374) Show SMILES CC(C)(C)c1ccc(Cc2cc(ccc2Cl)[C@@H]2O[C@H]([C@H](O)CO)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C23H29ClO5/c1-23(2,3)16-7-4-13(5-8-16)10-15-11-14(6-9-17(15)24)21-19(27)20(28)22(29-21)18(26)12-25/h4-9,11,18-22,25-28H,10,12H2,1-3H3/t18-,19-,20-,21+,22-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method				Bioorg Med Chem 21: 6282-91 (2013) Article DOI: 10.1016/j.bmc.2013.08.067 BindingDB Entry DOI: 10.7270/Q29G5P80
					More data for this Ligand-Target Pair