BindingDB PrimarySearch

null

SMILES: OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O

InChI Key: InChIKey=ADHSWFUIIRWNHD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50442512
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi 'Aldo Moro' di Bari Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 1941-3 (2014) Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi 'Aldo Moro' di Bari Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 1941-3 (2014) Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi 'Aldo Moro' di Bari Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 9 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 1941-3 (2014) Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi 'Aldo Moro' di Bari Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 1941-3 (2014) Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT
					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase (Arabidopsis thaliana)	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 min				J Agric Food Chem 56: 3193-9 (2008) Article DOI: 10.1021/jf800029t BindingDB Entry DOI: 10.7270/Q2N58Q73
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-14 (Homo sapiens (Human))	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi 'Aldo Moro' di Bari Curated by ChEMBL					Assay Description Inhibition of MMP14 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate...				Bioorg Med Chem 21: 6456-65 (2013) Article DOI: 10.1016/j.bmc.2013.08.054 BindingDB Entry DOI: 10.7270/Q2222W7K
					More data for this Ligand-Target Pair
Glutamine synthetase, chloroplastic (Zea mays)	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...				Pest Manag Sci 66: 51-8 (2010) Article DOI: 10.1002/ps.1830 BindingDB Entry DOI: 10.7270/Q2V40Z3P
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamine synthetase, chloroplastic (Zea mays)	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Inhibition of Zea mays cv. Jeff (maize) leaf glutamine synthetase using L-glutamate as substrate assessed as inorganic phosphate production after 20 ...				Pest Manag Sci 66: 51-8 (2010) Article DOI: 10.1002/ps.1830 BindingDB Entry DOI: 10.7270/Q2V40Z3P
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Pyrroline-5-carboxylate reductase (Arabidopsis thaliana)	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.68E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ferrara Curated by ChEMBL					Assay Description Inhibition of Arabidopsis thaliana P5C assessed as reduction in NADH oxidation incubated at 35 degC up to 10 min				J Agric Food Chem 56: 3193-9 (2008) Article DOI: 10.1021/jf800029t BindingDB Entry DOI: 10.7270/Q2N58Q73
University of Ferrara Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 14 (Homo sapiens (Human))	BDBM50442512 (CHEMBL2440433) Show SMILES OP(O)(=O)C(Nc1ccc(Cl)c(Cl)c1)P(O)(O)=O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi 'Aldo Moro' di Bari Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 14 preincubated for 15 mins by stopped flow CO2 hydration method				Bioorg Med Chem Lett 24: 1941-3 (2014) Article DOI: 10.1016/j.bmcl.2014.03.001 BindingDB Entry DOI: 10.7270/Q2PV6MWT
					More data for this Ligand-Target Pair