BDBM50442815 CHEMBL2440746

SMILES: CCCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1

InChI Key: InChIKey=RUKUHGXZSDHQDA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50442815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50442815 (CHEMBL2440746) Show SMILES CCCCOC(=O)c1cccc(c1)-c1cc(ccc1CN)C(=O)Nc1ccncc1 Show InChI InChI=1S/C24H25N3O3/c1-2-3-13-30-24(29)19-6-4-5-17(14-19)22-15-18(7-8-20(22)16-25)23(28)27-21-9-11-26-12-10-21/h4-12,14-15H,2-3,13,16,25H2,1H3,(H,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Amakem N.V. Curated by ChEMBL					Assay Description Inhibition of ROCK2 (unknown origin) using long S6 kinase peptide as substrate by radiometric assay				Bioorg Med Chem Lett 23: 6442-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.040 BindingDB Entry DOI: 10.7270/Q2BC411W
					More data for this Ligand-Target Pair