BDBM50443069 CHEMBL3086719
SMILES: COC(=O)N1CCC2(CC(O)(C2)C#Cc2cccc(C)c2)CC1
InChI Key: InChIKey=ILNMYSGPLVXPRM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50443069 (CHEMBL3086719) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 306 | n/a | n/a | n/a | n/a | n/a | n/a |
Merz Pharmaceuticals GmbH Curated by ChEMBL | Assay Description Negative allosteric modulation of human mGlu5 receptor expressed in CHO cells assessed as inhibition of L-quisqualate-induced intracellular calcium m... | Bioorg Med Chem Lett 23: 6370-6 (2013) Article DOI: 10.1016/j.bmcl.2013.09.059 BindingDB Entry DOI: 10.7270/Q2W37XRD | |||||||||||
More data for this Ligand-Target Pair |