BDBM50443151 CHEMBL3086325

SMILES: NC(=O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1

InChI Key: InChIKey=VOAYWJAHIYVVPX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50443151   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50443151 (CHEMBL3086325) Show SMILES NC(=O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1 |t:21| Show InChI InChI=1S/C18H17N5O2/c19-9-13-10-21-17(22-13)18(25)23-15-7-6-12(16(20)24)8-14(15)11-4-2-1-3-5-11/h4,6-8,10H,1-3,5H2,(H2,20,24)(H,21,22)(H,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of FMS (unknown origin)				Bioorg Med Chem Lett 23: 6363-9 (2013) Article DOI: 10.1016/j.bmcl.2013.09.061 BindingDB Entry DOI: 10.7270/Q2MP54RH
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse))	BDBM50443151 (CHEMBL3086325) Show SMILES NC(=O)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1 |t:21| Show InChI InChI=1S/C18H17N5O2/c19-9-13-10-21-17(22-13)18(25)23-15-7-6-12(16(20)24)8-14(15)11-4-2-1-3-5-11/h4,6-8,10H,1-3,5H2,(H2,20,24)(H,21,22)(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutical Research& Development LLC Curated by ChEMBL					Assay Description Inhibition of FMS in mouse BMDM cells				Bioorg Med Chem Lett 23: 6363-9 (2013) Article DOI: 10.1016/j.bmcl.2013.09.061 BindingDB Entry DOI: 10.7270/Q2MP54RH
					More data for this Ligand-Target Pair