BDBM50443983 CHEMBL3092299

SMILES: Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC(=O)N4CCCC(F)(F)C4)cc23)cc1Cl

InChI Key: InChIKey=CJVSLXNVNBNKOM-HNNXBMFYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50443983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50443983 (CHEMBL3092299) Show SMILES Fc1ccc(Nc2ncnc3cc(O[C@H]4CCOC4)c(NC(=O)N4CCCC(F)(F)C4)cc23)cc1Cl |r| Show InChI InChI=1S/C24H23ClF3N5O3/c25-17-8-14(2-3-18(17)26)31-22-16-9-20(32-23(34)33-6-1-5-24(27,28)12-33)21(10-19(16)29-13-30-22)36-15-4-7-35-11-15/h2-3,8-10,13,15H,1,4-7,11-12H2,(H,32,34)(H,29,30,31)/t15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	884	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of wild type EGFR (unknown origin) expressed in baculovirus expression system using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELIS...				Bioorg Med Chem 21: 7988-98 (2013) Article DOI: 10.1016/j.bmc.2013.09.049 BindingDB Entry DOI: 10.7270/Q2ZK5J4G
					More data for this Ligand-Target Pair