BDBM50444115 CHEMBL3093160

SMILES: Nc1ncc(cc1-c1nc2ccc(OCc3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1

InChI Key: InChIKey=ICUJBWBOFMJABJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM50444115 (CHEMBL3093160) Show SMILES Nc1ncc(cc1-c1nc2ccc(OCc3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C27H25FN6O2/c28-20-3-1-17(2-4-20)16-35-22-5-6-24-25(12-22)36-27(33-24)23-11-18(13-31-26(23)29)19-14-32-34(15-19)21-7-9-30-10-8-21/h1-6,11-15,21,30H,7-10,16H2,(H2,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of GRK-2 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...				Bioorg Med Chem Lett 23: 6711-6 (2013) Article DOI: 10.1016/j.bmcl.2013.10.036 BindingDB Entry DOI: 10.7270/Q2SX6FPP
					More data for this Ligand-Target Pair
G protein-coupled receptor kinase 5 (Homo sapiens (Human))	BDBM50444115 (CHEMBL3093160) Show SMILES Nc1ncc(cc1-c1nc2ccc(OCc3ccc(F)cc3)cc2o1)-c1cnn(c1)C1CCNCC1 Show InChI InChI=1S/C27H25FN6O2/c28-20-3-1-17(2-4-20)16-35-22-5-6-24-25(12-22)36-27(33-24)23-11-18(13-31-26(23)29)19-14-32-34(15-19)21-7-9-30-10-8-21/h1-6,11-15,21,30H,7-10,16H2,(H2,29,31)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of GRK-5 (unknown origin) preincubated with enzyme for 10 mins before adding peptide substrate and ATP measured after 1 hr by LANCE-TR-FRE...				Bioorg Med Chem Lett 23: 6711-6 (2013) Article DOI: 10.1016/j.bmcl.2013.10.036 BindingDB Entry DOI: 10.7270/Q2SX6FPP
					More data for this Ligand-Target Pair