BDBM50444159 CHEMBL3093400

SMILES: OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCN1CCOCC1)C(F)(F)F

InChI Key: InChIKey=AQZRDSIWABPBRF-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444159   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelial lipase (Homo sapiens (Human))	BDBM50444159 (CHEMBL3093400) Show SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)OCCN1CCOCC1)C(F)(F)F |r| Show InChI InChI=1S/C18H23F3N2O4/c19-18(20,21)13-1-2-16(15(11-13)17(24)25)23-4-3-14(12-23)27-10-7-22-5-8-26-9-6-22/h1-2,11,14H,3-10,12H2,(H,24,25)/t14-/m0/s1	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	659	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...				Bioorg Med Chem 21: 7724-34 (2013) Article DOI: 10.1016/j.bmc.2013.10.023 BindingDB Entry DOI: 10.7270/Q2P55PZ8
					More data for this Ligand-Target Pair