BDBM50444390 CHEMBL3094468

SMILES: CC[C@@H](Cc1ccc(O)c(C)c1C)NS(=O)(=O)c1c(C)cc(C)cc1C

InChI Key: InChIKey=JQDUVTPGLRBCNA-IBGZPJMESA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444390   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50444390 (CHEMBL3094468) Show SMILES CC[C@@H](Cc1ccc(O)c(C)c1C)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C21H29NO3S/c1-7-19(12-18-8-9-20(23)17(6)16(18)5)22-26(24,25)21-14(3)10-13(2)11-15(21)4/h8-11,19,22-23H,7,12H2,1-6H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assay				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50444390 (CHEMBL3094468) Show SMILES CC[C@@H](Cc1ccc(O)c(C)c1C)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C21H29NO3S/c1-7-19(12-18-8-9-20(23)17(6)16(18)5)22-26(24,25)21-14(3)10-13(2)11-15(21)4/h8-11,19,22-23H,7,12H2,1-6H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of progesterone receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assay				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50444390 (CHEMBL3094468) Show SMILES CC[C@@H](Cc1ccc(O)c(C)c1C)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C21H29NO3S/c1-7-19(12-18-8-9-20(23)17(6)16(18)5)22-26(24,25)21-14(3)10-13(2)11-15(21)4/h8-11,19,22-23H,7,12H2,1-6H3/t19-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mineralocorticoid receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assay				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50444390 (CHEMBL3094468) Show SMILES CC[C@@H](Cc1ccc(O)c(C)c1C)NS(=O)(=O)c1c(C)cc(C)cc1C |r| Show InChI InChI=1S/C21H29NO3S/c1-7-19(12-18-8-9-20(23)17(6)16(18)5)22-26(24,25)21-14(3)10-13(2)11-15(21)4/h8-11,19,22-23H,7,12H2,1-6H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human foreskin fibroblasts assessed as IL-1-mediated IL-6 synthesis after 24 hrs				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair