BDBM50444401 CHEMBL3094478

SMILES: CCC(Cc1cc(Cl)cc(Cl)c1)NS(=O)(=O)c1c(C)cc(C)cc1C

InChI Key: InChIKey=YBIHCFXAMSLIHT-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50444401 (CHEMBL3094478) Show SMILES CCC(Cc1cc(Cl)cc(Cl)c1)NS(=O)(=O)c1c(C)cc(C)cc1C Show InChI InChI=1S/C19H23Cl2NO2S/c1-5-18(10-15-8-16(20)11-17(21)9-15)22-25(23,24)19-13(3)6-12(2)7-14(19)4/h6-9,11,18,22H,5,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of glucocorticoid receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assay				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50444401 (CHEMBL3094478) Show SMILES CCC(Cc1cc(Cl)cc(Cl)c1)NS(=O)(=O)c1c(C)cc(C)cc1C Show InChI InChI=1S/C19H23Cl2NO2S/c1-5-18(10-15-8-16(20)11-17(21)9-15)22-25(23,24)19-13(3)6-12(2)7-14(19)4/h6-9,11,18,22H,5,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of progesterone receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assay				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50444401 (CHEMBL3094478) Show SMILES CCC(Cc1cc(Cl)cc(Cl)c1)NS(=O)(=O)c1c(C)cc(C)cc1C Show InChI InChI=1S/C19H23Cl2NO2S/c1-5-18(10-15-8-16(20)11-17(21)9-15)22-25(23,24)19-13(3)6-12(2)7-14(19)4/h6-9,11,18,22H,5,10H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of mineralocorticoid receptor (unknown origin) expressed in baculovirus-infected insect cells by fluorescence polarization assay				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50444401 (CHEMBL3094478) Show SMILES CCC(Cc1cc(Cl)cc(Cl)c1)NS(=O)(=O)c1c(C)cc(C)cc1C Show InChI InChI=1S/C19H23Cl2NO2S/c1-5-18(10-15-8-16(20)11-17(21)9-15)22-25(23,24)19-13(3)6-12(2)7-14(19)4/h6-9,11,18,22H,5,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human foreskin fibroblasts assessed as IL-1-mediated IL-6 synthesis after 24 hrs				Bioorg Med Chem Lett 23: 6645-9 (2013) Article DOI: 10.1016/j.bmcl.2013.10.047 BindingDB Entry DOI: 10.7270/Q2VQ345N
					More data for this Ligand-Target Pair