BDBM50444456 2-Hydrazinylbenzo[D]Thiazole::CHEMBL1933308

SMILES: NNc1nc2ccccc2s1

InChI Key: InChIKey=JYSUYJCLUODSLN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444456   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Indoleamine 2,3-dioxygenase 1 (Mus musculus)	BDBM50444456 (2-Hydrazinylbenzo[D]Thiazole | CHEMBL1933308) Show SMILES NNc1nc2ccccc2s1 Show InChI InChI=1S/C7H7N3S/c8-10-7-9-5-3-1-2-4-6(5)11-7/h1-4H,8H2,(H,9,10)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of mouse IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrs				Bioorg Med Chem 21: 7595-603 (2013) Article DOI: 10.1016/j.bmc.2013.10.037 BindingDB Entry DOI: 10.7270/Q2377B6F
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50444456 (2-Hydrazinylbenzo[D]Thiazole | CHEMBL1933308) Show SMILES NNc1nc2ccccc2s1 Show InChI InChI=1S/C7H7N3S/c8-10-7-9-5-3-1-2-4-6(5)11-7/h1-4H,8H2,(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 using L-tryptophan as substrate after 1 hr				Bioorg Med Chem 21: 7595-603 (2013) Article DOI: 10.1016/j.bmc.2013.10.037 BindingDB Entry DOI: 10.7270/Q2377B6F
					More data for this Ligand-Target Pair
Indoleamine 2,3-dioxygenase (Homo sapiens (Human))	BDBM50444456 (2-Hydrazinylbenzo[D]Thiazole | CHEMBL1933308) Show SMILES NNc1nc2ccccc2s1 Show InChI InChI=1S/C7H7N3S/c8-10-7-9-5-3-1-2-4-6(5)11-7/h1-4H,8H2,(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of human IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrs				Bioorg Med Chem 21: 7595-603 (2013) Article DOI: 10.1016/j.bmc.2013.10.037 BindingDB Entry DOI: 10.7270/Q2377B6F
					More data for this Ligand-Target Pair