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SMILES: COc1cc(ccc1[C@H]1CCc2cncn12)C#N

InChI Key: InChIKey=HIXAIFSCQRUDBN-CYBMUJFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50444555   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cytochrome P450 11B2, mitochondrial


(Homo sapiens (Human))		BDBM50444555
PNG
(CHEMBL3099694)
Show SMILES COc1cc(ccc1[C@H]1CCc2cncn12)C#N |r|
Show InChI InChI=1S/C14H13N3O/c1-18-14-6-10(7-15)2-4-12(14)13-5-3-11-8-16-9-17(11)13/h2,4,6,8-9,13H,3,5H2,1H3/t13-/m1/s1
PDB

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Novartis Institutes for BioMedical Research

Curated by ChEMBL


Assay Description
Inhibition of CYP11B2 in human NCI-H295R cells assessed as inhibition of angiotensin-2-induced aldosterone production after 24 hrs by RIA

ACS Med Chem Lett 4: 1203-7 (2013)


Article DOI: 10.1021/ml400324c
BindingDB Entry DOI: 10.7270/Q2NZ8938
More data for this
Ligand-Target Pair