BDBM50445236 CHEMBL3102947

SMILES: COc1ccc(OC)c(c1)-c1cnc2[nH]cc(-c3ccc(OC)c(OC)c3)c2c1

InChI Key: InChIKey=PGGSIXVEVLPEAI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50445236   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (RAT)	BDBM50445236 (CHEMBL3102947) Show SMILES COc1ccc(OC)c(c1)-c1cnc2[nH]cc(-c3ccc(OC)c(OC)c3)c2c1 Show InChI InChI=1S/C23H22N2O4/c1-26-16-6-8-20(27-2)17(11-16)15-9-18-19(13-25-23(18)24-12-15)14-5-7-21(28-3)22(10-14)29-4/h5-13H,1-4H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
UPR 2301, CNRS Curated by ChEMBL					Assay Description Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein c...				J Med Chem 56: 9569-85 (2014) Article DOI: 10.1021/jm401049v BindingDB Entry DOI: 10.7270/Q2BG2QFT
					More data for this Ligand-Target Pair